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Mutation of H143 to an asparagine resulted while in the remarkable loss of catalytic activity plus a reasonable increase in the K
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s) are serpent princesses of placing beauty. The dynasties of Manipur in northeastern India, the Pallavas in southern India, as well as the ruling household of Funan (historic Indochina) Each individual claimed an origin during the union of a human being in addition to a nagi
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m profile (Desk 3). These effects are entirely per the conclusion that the next ionization observed within the pH-rate profile for log k
There are a substantial quantity of problems regarding the mechanism for substrate hydrolysis by NagA which have been unresolved. It can be unclear how the divalent cation binds in the active web-site of NagA And the way the h2o molecule is activated for nucleophilic attack on the amide bond. The disparity in the metal ligation strategies amongst the E. coli
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